TB is a treatable disease if you follow your doctor's treatment plan. If TB is not treated properly, TB bacteria can become resistant to one or multiple drugs used in treatment. When the bacteria become resistant to multiple drugs, it is known as multidrug-resistant tuberculosis (or MDR-TB). Treatment plans for MDR-TB involve another group of antibiotics called second-line antibiotics. These drugs vary in duration and can also have negative side effects, but they are necessary to cure MDR-TB. Work closely with your doctor or healthcare provider to develop a plan and then stick to it.